Saturday - May 8, 2021
Leicester City - Newcastle United at 3:00am |
| Leeds United - Tottenham Hotspur at 7:30pm |
| Sheffield United - Crystal Palace at 10:00pm |
Sunday - May 9, 2021
Manchester City - Chelsea at 12:30am |
| Liverpool - Southampton at 3:15am |
| Wolverhampton Wanderers - Brighton & Hove Albion FC at 7:00pm |
| Aston Villa - Manchester United at 9:05pm |
| West Ham United - Everton at 11:30pm |
Monday - May 10, 2021
Arsenal - West Bromwich Albion at 2:00am |
Tuesday - May 11, 2021
Fulham - Burnley FC at 3:00am |
Wednesday - May 12, 2021
Manchester United - Leicester City at 1:00am |
| Southampton - Crystal Palace at 3:15am |
Thursday - May 13, 2021
Chelsea - Arsenal at 3:15am |
Friday - May 14, 2021
Aston Villa - Everton at 1:00am |
| Manchester United - Liverpool at 3:15am |
Saturday - May 15, 2021
Newcastle United - Manchester City at 3:00am |
| Burnley FC - Leeds United at 7:30pm |
| Southampton - Fulham at 10:00pm |
Sunday - May 16, 2021
Brighton & Hove Albion FC - West Ham United at 3:00am |
| Crystal Palace - Aston Villa at 7:00pm |
| Tottenham Hotspur - Wolverhampton Wanderers at 9:05pm |
| West Bromwich Albion - Liverpool at 11:30pm |
Monday - May 17, 2021
Everton - Sheffield United at 2:00am |
Wednesday - May 19, 2021
Manchester United - Fulham at 1:00am |
| Southampton - Leeds United at 1:00am |
| Brighton & Hove Albion FC - Manchester City at 2:00am |
| Chelsea - Leicester City at 3:15am |
Thursday - May 20, 2021
Everton - Wolverhampton Wanderers at 1:00am |
| Newcastle United - Sheffield United at 1:00am |
| Tottenham Hotspur - Aston Villa at 1:00am |
| Crystal Palace - Arsenal at 2:00am |
| Burnley FC - Liverpool at 3:15am |
| West Bromwich Albion - West Ham United at 3:15am |
Sunday - May 23, 2021
Arsenal - Brighton & Hove Albion FC at 11:00pm |
| Aston Villa - Chelsea at 11:00pm |
| Fulham - Newcastle United at 11:00pm |
| Leeds United - West Bromwich Albion at 11:00pm |
| Leicester City - Tottenham Hotspur at 11:00pm |
| Liverpool - Crystal Palace at 11:00pm |
| Manchester City - Everton at 11:00pm |
| Sheffield United - Burnley FC at 11:00pm |
| West Ham United - Southampton at 11:00pm |
| Wolverhampton Wanderers - Manchester United at 11:00pm |
